ABOUT RHYTHM

Pioneering a path forward at Rhythm

Rhythm Pharmaceuticals is a global commercial-stage biopharmaceutical company focused on rare neuroendocrine diseases. Our people immerse themselves in our vision, mission and values so we can create innovations that achieve meaningful positive impact on those living with rare neuroendocrine diseases.

Our vision

Patients with rare neuroendocrine diseases are able to live their fullest lives and are transformed through optimal, stigma-free care.

Our mission

To transform the lives of patients with rare neuroendocrine diseases by rapidly advancing care and precision medicines that address the root cause.

Our values

We are inspired to tackle tough challenges and have the courage to ask bold questions.

We are committed to advancing scientific understanding to improve patients’ lives.

We are eager to learn and adapt.

We believe collaboration and ownership are foundational for Rhythm’s success.

We value the unique contribution each individual brings to furthering our mission.

Our path to help transform the care of rare neuroendocrine diseases

Explore our step-by-step path forward:

2008

Founded in Boston

2011

First patients with rare melanocortin-4 receptor (MC4R) pathway diseases on treatment

2016

Phase 2 results in POMC deficiency published in the New England Journal of Medicine 

2017

Initial Public Offering completed on Nasdaq

2018

Phase 2 results in LEPR deficiency published in Nature Medicine

2019

Phase 3 trial in POMC deficiency initiated

2020

FDA approves precision medicine for the treatment of obesity and the control of hunger associated with for POMC and LEPR deficiency

2021

European Commission authorizes precision medicine for the treatment of obesity and the control of hunger associated with POMC, PSCK1 and LEPR deficiency

2022

Precision medicine approved for BBS in US and Europe

2023

Xinvento acquired

Initiates Phase 3 trial in acquired hypothalamic obesity

2024

First-ever patients dosed with RM-718

Acquired oral MC4R agonist LB54640 from LG Chem Life Sciences

2026

Precision medicine approved for the treatment of acquired hypothalamic obesity (aHO) in US and Europe

Our locations

Rhythm international presence and partnerships

Legend

Rhythm Presence
Rhythm Partnership

Rhythm Pharmaceuticals Finland

Rhythm Pharmaceuticals Norway

Rhythm Pharmaceuticals Sweden

Rhythm Pharmaceuticals Denmark

Rhythm Pharmaceuticals Ireland

Rhythm Pharmaceuticals Netherlands

Radarweg 29,
1043 NX Amsterdam
The Netherlands

Rhythm Pharmaceuticals UK Ltd

London

Rhythm Pharmaceuticals Belgium

Central and Eastern Europe (Exceed Orphan)

Rhythm Pharmaceuticals Luxembourg

Rhythm Pharmaceuticals France

121 rue d'Aguesseau – 92100 Boulogne-Billancourt

Rhythm Pharmaceuticals Austria

Rhythm Pharmaceuticals Germany

Maximilianstr. 35a, D-80539 München, Germany

Rhythm Pharmaceuticals Switzerland

Rhythm Pharmaceuticals Italy

Trispera

Izzet Pasa Mh. Yeni Yol Cd. Nurol Tower No:3/336 eOfis 34381 Sisli - Istanbul, Türkiye

Rhythm Pharmaceuticals Spain

Rhythm Pharmaceuticals Portugal

Greece (Ariti)

Rhythm Pharmaceuticals Japan

Israel (Medison)

Gulf Cooperation Council (Genpharm)

Rhythm Pharmaceuticals Argentina